Lihua Geng Selected Research

fucoidan

2/2024	Low molecular weight fucoidan LF2 improves the immunosuppressive tumor microenvironment and enhances the anti-pancreatic cancer activity of oxaliplatin.
1/2024	Opportunities and challenges of fucoidan for tumors therapy.
11/2023	Low molecular weight fucoidan (LMWF) restores diabetic endothelial glycocalyx by targeting Neuraminidase2 (NEU2): a new therapy target in glycocalyx shedding.
5/2023	Isolation, Characterization, and Anti-Idiopathic Pulmonary Fibrosis Activity of a Fucoidan from Costaria costata.
12/2022	Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer.
9/2022	Low molecular weight fucoidan alleviates cerebrovascular damage by promoting angiogenesis in type 2 diabetes mice.
12/2021	Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota.
12/2021	Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition.
2/2020	Comparative Study of Fucoidan from Saccharina japonica and Its Depolymerized Fragment on Adriamycin-Induced Nephrotic Syndrome in Rats.
1/2019	Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies.

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Lihua Geng Research Topics

Disease

4	Neoplasms (Cancer) 02/2024 - 01/2019
3	Fibrosis (Cirrhosis) 05/2023 - 01/2019
2	Inflammation (Inflammations) 11/2023 - 05/2023
1	Pancreatic Neoplasms (Pancreatic Cancer) 02/2024
1	Neoplasm Metastasis (Metastasis) 01/2024
1	Carcinogenesis 01/2024
1	Diabetes Complications 11/2023
1	Diabetic Angiopathies (Diabetic Angiopathy) 11/2023
1	Wounds and Injuries (Trauma) 11/2023
1	Idiopathic Pulmonary Fibrosis 05/2023
1	Infections 01/2023
1	Colonic Neoplasms (Colon Cancer) 12/2022
1	Colorectal Neoplasms (Colorectal Cancer) 12/2022
1	Type 2 Diabetes Mellitus (MODY) 09/2022
1	Insulin Resistance 12/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2021
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2021
1	Nephrotic Syndrome (Syndrome, Nephrotic) 02/2020
1	Proteinuria 02/2020
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2019
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019
1	Sclerosis 01/2019
1	Acute Kidney Injury (Acute Renal Failure) 01/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2019
1	Body Weight (Weight, Body) 03/2018

Drug/Important Bio-Agent (IBA)

10	fucoidanIBA 02/2024 - 01/2019
2	Triglycerides (Triacylglycerol)IBA 11/2023 - 02/2020
2	Insulin (Novolin)FDA Link 11/2023 - 12/2021
2	Bleomycin (Blenoxane)FDA LinkGeneric 05/2023 - 12/2021
2	AntioxidantsIBA 02/2020 - 01/2019
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 02/2024
1	Uric Acid (Urate)IBA 11/2023
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2023
1	Messenger RNA (mRNA)IBA 11/2023
1	Glycoproteins (Glycoprotein)IBA 01/2023
1	Proteins (Proteins, Gene)FDA Link 01/2023
1	Capecitabine (Xeloda)FDA Link 12/2022
1	LipidsIBA 12/2021
1	Metformin (Glucophage)FDA LinkGeneric 12/2021
1	Blood Glucose (Blood Sugar)IBA 12/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2020
1	Urea (Carbamide)FDA LinkGeneric 02/2020
1	NitrogenIBA 02/2020
1	CreatinineIBA 02/2020
1	CholesterolIBA 02/2020
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 03/2018

Therapy/Procedure

2	Immunomodulation 02/2024 - 01/2019
2	Drug Therapy (Chemotherapy) 02/2024 - 12/2022
2	Therapeutics 01/2024 - 12/2022
1	Immunotherapy 12/2022
1	Oral Administration 02/2020